Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Serine Racemase Mouse, Unlabeled, Clone: 29, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 612052

 View more versions of this product

Catalog No. BDB612052

Add to cart



The majority of synapses in the central nervous system utilize glutamate as a neurotransmitter to produce rapid neuronal excitation. Glutamate has a diverse array of receptors that can be categorized into two groups: ionotropic and metabotropic. The ionotropic receptors are subdivided into two distinct types: 1) receptors for N-methyl D-aspartate (NMDAR) and 2) non-NMDA receptors for AMPA and kainate. NMDA receptors require coactivation at both glutamate and glycine sites. D-serine is a D-amino acid found in mammalian tissues that can act as a potent ligand for the glycine site on NMDA receptors. D-serine is made by the enzyme serine racemase, which is a member of the pyridoxal-5′ phosphate (PLP)-dependent enzyme family. Serine racemase mRNA is expressed in brain and liver, and serine racemase protein is expressed in glial cells. Degradation of D-serine by D-amino acid oxidase attenuates NMDA receptor-mediated calcium influx, and implicates D-serine as an endogenouse modulator of NMDA receptor function. Thus, glial cell production of D-serine via serine racemase activity may be an important system for modulation of synaptic transmission.

Host Species: Mouse
Clone: 29
Isotype: IgG1
Species Reactivity [for Features Main]: Mouse
Immunogen: Mouse serine racemase aa. 127-248

Immunofluorescence, Western Blotting



Serine Racemase
Affinity Purified
Mouse serine racemase aa. 127-248
Cell Biology
Murine, Rat
Western Blot
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Store undiluted at -20°C.
Product Certifications


Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit

For Research Use Only.