HTR7 Rabbit anti-Canine, Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA141122
This antibody is predicted to react with porcine samples based on sequence homology. The immunogen sequence is 93% conserved with canine 5-HT7Ra/b, and 81% conserved with porcine 5-HT7R.Receptors for serotonin (5-hydroxytryptamine, 5-HT) are classified into seven major classes (5-HTR1-7), based on structural, functional and pharmacological criteria (Hoyer et al, 1994). The 5-HT7 receptor (5-HT7R) is a seven-transmembrane-domain G-protein-coupled receptor that has important roles in regulating diverse biological process in the central and peripheral nervous systems (reviewed in Hedlund and Sutcliffe, 2004). Receptors for serotonin (5-hydroxytryptamine, 5-HT) are classified into seven major classes (5-HT1-7), based on structural, functional and pharmacological criteria (Hoyer et al, 1994). Sequence alignment shows a high degree of interspecies 5-HT7R homology (>90%), and a low homology with other 5-HTRs.
|Synthetic peptide corresponding to residues 13-28 of rat 5-HT7R.|
|Canine, Human, Mouse, Rat|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|PBS with 0.05% sodium azide|
|P34969, P32304, P32305|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|15566, 3363, 477762, 65032|
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