SERPINC1, Mouse, Clone: 2B12, Abnova™

Mouse monoclonal antibody raised against a full-length recombinant SERPINC1.

Manufacturer: Abnova Corporation H00000462M02

Catalog No. 89-016-230

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    Specifications

    Antigen SERPINC1
    Applications Enzyme Linked Immunosorbent Assay,Western Blotting
    Clone 2B12
    Conjugate Unlabeled
    Cross Reactivity Human
    Description serpin peptidase inhibitor, clade C (antithrombin), member 1
    Format Liquid
    Formulation In 1X PBS, pH 7.4
    Gene SERPINC1
    Gene Accession No. BC022309
    Gene Alias AT3, ATIII, MGC22579
    Gene Symbols SERPINC1
    Host Species Mouse
    Immunogen SERPINC1 (AAH22309, 1 a.a. ∽260 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26kDa
    Isotype IgG2b, κ
    Quantity 100μg
    Regulatory Status RUO
    Species Reactivity Human
    Storage Requirements Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
    Primary or Secondary Primary
    Monoclonal or Polyclonal Monoclonal
    Gene ID (Entrez) 462

    The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency. [provided by RefSeq

    Sequence: MYSNVIGTVTSGKRKVYLLSLLLIGFWDCVTCHGSPVDICTAEPRDIPMNPMCIYRSPEKKATEDEGSEQKIPEATNRRVWELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKANRPFLVFIREVPLNTIIFMGRVANPCVK

  • Description & Specifications

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