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Neuroserpin Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523892

Catalog No. PIPA523892


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Description

Description

This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a domitly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Specifications

Specifications

Neuroserpin
Polyclonal
PBS with 0.09% sodium azide
Q99574
PI12, neuroserpin, PI-12, neuroserpin, peptidase inhibitor 12, serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 1, serpin I1
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
5274
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
Unconjugated
SERPINI1
Liquid
SERPINI1
KLH conjugated synthetic peptide between 19-45 amino acids from the N-terminal region of human SERPINI1
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Documents
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