Neuroserpin Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA523892
DescriptionThis gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a domitly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified.
|PBS with 0.09% sodium azide|
|PI12, neuroserpin, PI-12, neuroserpin, peptidase inhibitor 12, serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 1, serpin I1|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot|
|KLH conjugated synthetic peptide between 19-45 amino acids from the N-terminal region of human SERPINI1|
|Antigen affinity chromatography|
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