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SF3B4 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA528441

Catalog No. PIPA528441


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Description

Description

PA5-28441 targets SF3B4 in IF and WB applications and shows reactivity with Human and mouse samples. The PA5-28441 immunogen is synthetic peptide corresponding to a region within amino acids 1 and 44 of Human SF3B4. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.
Specifications

Specifications

SF3B4
Polyclonal
Unconjugated
SF3B4
Liquid
SF3B4
Synthetic peptide corresponding to a region within amino acids 1 and 44 of Human SF3B4
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunocytochemistry, Immunofluorescence, Western Blot
1.0 mg/mL
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Q15427, Q8QZY9
Hsh49, SAP49, SF3b49, SAP 49, SF3b50, pre-mRNA splicing factor SF3b 49 kDa subunit, pre-mRNA-splicing factor SF3b 49 kDa subunit, spliceosomal protein, spliceosome-associated protein (U2 snRNP), spliceosome-associated protein 49, splicing factor 3B subunit 4
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
10262, 107701
Documents
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