SH3BP2 Sheep anti-Mouse, Polyclonal, Invitrogen™
Sheep Polyclonal Antibody
Manufacturer: Invitrogen PA112492
A suggested positive control for this product is recombit 3BP2 protein.3BP2 (SH3 binding protein 2) was identified as a protein binding to the SH3 domain of the Abl proto-oncogene. Murine 3BP2 cDNA encodes a 559 amino acid protein of 85 kDa consisting of an N-terminal PH domain, a C-terminal SH2 domain and intervening proline-rich sequences. 3BP2 interacts via its Sh2 domain with Syk family protein tyrosine kinases Syk, Zap70, Grb2, Cbl, PLCg 1 and LAT in T lymphocytes and contributes to the transcriptional activation of NF-AT and AP-1.
|PBS with 0.08% sodium azide|
|CRBM, CRPM, RES4-23|
|-20° C, Avoid Freeze/Thaw Cycles|
|SH2 domain of the 3BP2 protein fused to GST.|
|Ammonium sulfate precipitation|
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