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SHANK1 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA528633

Catalog No. PIPA528633


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Description

Description

PA5-28633 targets SHANK1 in IHC (P) and WB applications and shows reactivity with Human samples. The PA5-28633 immunogen is synthetic peptide corresponding to a region within amino acids 2100 and 2161 of Human SHANK1. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic junction.
Specifications

Specifications

SHANK1
Polyclonal
Unconjugated
SHANK1
Liquid
SHANK1
Synthetic peptide corresponding to a region within amino acids 2100 and 2161 of Human SHANK1
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
0.53 mg/mL
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Q9Y566, D3YZU1
SPANK-1, SSTRIP, synamon, SH3 and multiple ankyrin repeat domains protein 1, SSTR-interacting protein, somatostatin receptor-interacting protein
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
243961, 50944
Documents
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