SHANK1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA14180
PA1-4180 detects SHANK1a in human, rat, and mouse samples. PA1-4180 has been successfully used in Western blot, immunofluorescence, and immunofluoresence procedures. By Western blot this antibody detects a ~212 kDa protein representing SHANK1a in rat brain lysate. The PA1-4180 immunogen is a synthetic peptide corresponding to the C-terminal residues S(1951) G P I Y P G L F D I R S S(1964) of rat Shank1a. Maintain at 4°C for 3 months or at -20°C for longer periods. Avoid freeze/thaw cycles.Shank is a novel family of postsynaptic density proteins (PSD) that bind to PSD-95-associated protein GKAP. Its putative function is to act as a scaffold protein in the PSD to cross-link NMDA receptors/PSD-95 complexes and couple them to regulators of the actin cytoskeleton. Shank1a is a splice variant of Shank1.
|Synthetic peptide corresponding to the C-terminal residues S(1951) G P I Y P G L F D I R S S(1964) of rat Shank1a.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|Immunofluorescence, Immunohistochemistry, Western Blot|
|PBS with 0.02% sodium azide|
|Q9Y566, D3YZU1, Q9WV48|
|Shank1a, Spank1, Sstrip|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|243961, 50944, 78957|
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