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SHANK2 Mouse anti-Human, Clone: 711924, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524331

Catalog No. PIMA524331


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Description

Description

Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.

This gene encodes a protein that is a member of the Shank family of synaptic proteins that may function as molecular scaffolds in the postsynaptic density of excitatory synapses. Shank proteins contain multiple domains for protein-protein interaction, including ankyrin repeats, and an SH3 domain. This particular family member contains a PDZ domain, a consensus sequence for cortactin SH3 domain-binding peptides and a sterile alpha motif. The alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank-interacting proteins in the postsynaptic densities of the adult and developing brain. Alterations in the encoded protein may be associated with susceptibility to autism spectrum disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014].
Specifications

Specifications

SHANK2
Monoclonal
0.2 mg/mL
PBS with 5% trehalose and No Preservative
Q9UPX8
AUTS17, CORTBP1, CTTNBP1, ProSAP1, SPANK-3, AUTS17, cortactin binding protein 1, cortactin SH3 domain-binding protein, Cortactin-binding protein 1, CortBP1, CORTBP1CTTNBP1, GKAP/SAPAP interacting protein, KIAA1022, proline-rich synapse associated protein 1, Proline-rich synapse-associated protein 1, ProSAP1, PROSAP1, SH3 and multiple ankyrin repeat domains 2, SH3 and multiple ankyrin repeat domains protein 2, SHANK, Shank2, SPANK-3
Mouse
IgG1
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
22941
Immunohistochemistry (Paraffin)
711924
Unconjugated
SHANK2
Lyophilized
SHANK2
E. coli-derived recombit human SHANK2 Lys849-Thr1029
Protein A/G
RUO
Antibody
Monoclonal
Human
Documents
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