MilliporeSigma anti-Shc, Polyclonal
Rabbit Polyclonal Antibody
Manufacturer: MilliporeSigma ST103350UG
Specifically detects Shc Clone: in Human, Mouse, Rat samples, and it is validated for ELISA, Immunocytochemistry, Immunohistochemistry, ImmunoprecipitationShc is an SH2-PTB domain adaptor protein that links various tyrosine kinases to Ras by recruiting the Grb2/SOS complex to the plasma membrane. Note that the~66kDa isoform is not typically expressed in hematapoetic cells.
|Recognizes the ∽46, ∽55, and ∽66kDa isoforms of Shc in EGF-treated A431 cells.|
|ELISA, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation|
|a recombinant protein consisting of the Sh2 domain of human Shc, fused to GST|
|Human, Murine, Rat|
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