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MilliporeSigma™ anti-Shc, Polyclonal

Rabbit Polyclonal Antibody

Manufacturer:  MilliporeSigma™ ST103350UG

Catalog No. ST103350UG


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Description

Description

Specifically detects Shc Clone: in Human, Mouse, Rat samples, and it is validated for ELISA, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation

Shc is an SH2-PTB domain adaptor protein that links various tyrosine kinases to Ras by recruiting the Grb2/SOS complex to the plasma membrane. Note that the~66kDa isoform is not typically expressed in hematapoetic cells.
Specifications

Specifications

Shc
Unconjugated
Rabbit
IgG
RUO
Primary
Recognizes the ∽46, ∽55, and ∽66kDa isoforms of Shc in EGF-treated A431 cells.
ELISA, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation
purified
a recombinant protein consisting of the Sh2 domain of human Shc, fused to GST
50μg
−20°C
Polyclonal
Human, Murine, Rat
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