Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

ShcC Mouse, Unlabeled, Clone: 23, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 610642

 View more versions of this product

Catalog No. BDB610642


Add to cart

Description

Description

Mammalian ShcA is expressed as three proteins of 46kDa, 52kDa, and 66kDa. Each protein contains a C-terminal SH2 domain, a central glycine/proline rich sequence, and an N-terminal phosphotyrosine-binding domain (PTB). All three Shc proteins become tyrosine phosphorylated by activated growth factor receptors and oncogene tyrosine kinases. Two additional murine genes with Shc homology have been identified and named ShcB and ShcC. The ShcC gene encodes a protein of 475 amino acids and mobility of 55kDa. Additional immunoreactive proteins have been observed with apparent molecular weights of 69kDa and 100kDa. These could be due to extended 5 ft. sequences in the ShcC gene. In contrast to widely distributed ShcA proteins, expression of ShcC is restricted to the nervous system and spleen.

Immunofluorescence, Immunoprecipitation, Western Blotting

Specifications

Specifications

ShcC
23
Unconjugated
Affinity Purified
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
50μg
Cell Biology
Primary
Human, Murine, Rat
Western Blot
250μg/mL
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Murine
IgG1
RUO
Store undiluted at -20°C.
Monoclonal
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit

For Research Use Only.