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SHMT1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527858

Catalog No. PIPA527858


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Description

Description

PA5-27858 targets SHMT1 in WB applications and shows reactivity with Human samples. The PA5-27858 immunogen is recombit protein fragment corresponding to a region within amino acids 1 and 240 of Human SHMT1. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

This gene encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. Additional transcript variants have been described, but their biological validity has not been determined.
Specifications

Specifications

SHMT1
Polyclonal
Unconjugated
SHMT1
Liquid
SHMT1
Recombit protein fragment corresponding to a region within amino acids 1 and 240 of Human SHMT1
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Western Blot
1 mg/mL
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
P34896
CSHMT, SHMT, 14 kDa protein, cytoplasmic serine hydroxymethyltransferase, glycine hydroxymethyltransferase, serine hydroxymethyltransferase, cytosolic, serine methylase
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
6470
Documents
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