SHP2 Goat anti-Human, Mouse, Polyclonal, Invitrogen
Goat Polyclonal Antibody
Manufacturer: Invitrogen PA517956
This antibody is predicted to react with bovine, porcine and rat based on sequence homology.The protein encoded by this gene is a member of the protein tyrosine phosphatase family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noo syndrome as well as acute myeloid leukemia.
|Synthetic peptide sequence (YENVGLMQQQKSFR) corresponding to the C-terminus amino acids of PTPN11|
|Antigen affinity chromatography|
|Immunohistochemistry (Paraffin), Western Blot|
|TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3|
|PTPN11; SHP2; protein tyrosine phosphatase, non-receptor type 11 (Noo syndrome 1); CFC; NS1; BPTP3; PTP2C; SHP-2; PTP-1D; SH-PTP2; SH-PTP3; Noo syndrome 1; protein-tyrosine phosphatase 2C; protein tyrosine phosphatase, non-receptor type 11; MGC14433; protein tyrosine phosphatase-2|
|-20° C, Avoid Freeze/Thaw Cycles|
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