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SHP2 Goat anti-Human, Mouse, Polyclonal, Invitrogen™

Goat Polyclonal Antibody

Manufacturer:  Invitrogen PA517956

Catalog No. PIPA517956


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Description

Description

This antibody is predicted to react with bovine, porcine and rat based on sequence homology.

The protein encoded by this gene is a member of the protein tyrosine phosphatase family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noo syndrome as well as acute myeloid leukemia.
Specifications

Specifications

SHP2
Polyclonal
Unconjugated
PTPN11
Liquid
PTPN11
Synthetic peptide sequence (YENVGLMQQQKSFR) corresponding to the C-terminus amino acids of PTPN11
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunohistochemistry (Paraffin), Western Blot
0.5 mg/mL
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Q06124, P35235
PTPN11; SHP2; protein tyrosine phosphatase, non-receptor type 11 (Noo syndrome 1); CFC; NS1; BPTP3; PTP2C; SHP-2; PTP-1D; SH-PTP2; SH-PTP3; Noo syndrome 1; protein-tyrosine phosphatase 2C; protein tyrosine phosphatase, non-receptor type 11; MGC14433; protein tyrosine phosphatase-2
Goat
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
19247, 5781
SDS
Documents
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