Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

SIAH1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA112861

Catalog No. 01-675-841


Add to cart

Description

Description

A suggested positive control for this product is human brain lysate.

Seven in absentia homolog 1 (SIAH-1) is a member of the RINGfinger- containing E3 ubiquitin ligases. Alpha-synuclein and synphilin-1 are substrates of SIAH-1. Both proteins are involved in the development of Parkinson ft.s disease (PD). Mutations in Parkin, another E3 ubiquitin ligase which ubiquinates synphilin-1 and glycosylated alpha-synuclein, have been defined as a major cause of autosomal recessive PD. The role of SIAH-1 in PD is highlighted by the fact that SIAH-1 is a component of the Lewy bodies and plays a role in apoptosis caused by nitric oxide (NO) induced oxidative stress.
Specifications

Specifications

SIAH1
Polyclonal
Unconjugated
SIAH1
Liquid
SIAH1
Synthetic peptide corresponding to human SIAH-1.
Ammonium sulfate precipitation
RUO
Antibody
Polyclonal
Human
Western Blot
1 mg/mL
PBS with 0.08% sodium azide
Q8IUQ4
HUMSIAH, Siah-1, Siah-1a, hSIAH1
Rabbit
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
6477
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit