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SIAH1, Polyclonal, Invitrogen™

Goat Polyclonal Antibody

Manufacturer:  Invitrogen PA131497

Catalog No. PIPA131497

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of ParkinsoNULLs disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.

PA1-31497 detects SIAH1 from human samples. Expected to cross react with rat and mouse samples due to sequence homology. PA1-31497 has been successfully used in Western blot applications.The PA1-31497 immunogen is a peptide with sequence SRQTATALPTGTSKC, from N Terminus of the protein sequence according to NP_003022
Specifications

Specifications

SIAH1
Polyclonal
Unconjugated
SIAH1
Purified
SIAH1, SIAH1A
Peptide with sequence SRQTATALPTGTSKC, from N Terminus of the protein sequence according to NP_003022
IgG fraction
RUO
Antibody
Polyclonal
Human, Murine, Rat
Western Blot
0.5mg/mL
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Q8IUQ4, P61092, Q920M9
FLJ08065, SIAH1A
Goat
IgG
50μg
Avoid Freeze/Thaw Cycles
Primary
6477
Documents
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