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SIN3B Mouse anti-Human, Clone: 2C11, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA521444

Catalog No. PIMA521444


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Description

Description

Peptide Sequence: HKMVFIVNSE DYMYRRGTLC RAKQVQPLVL LRHHQHFEEW HSRWLEDNVT VEAASLVQDW LMGEEDEDMV PCKTLCETVH VHGLPVTRYR VQYSRRPA

Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.
Specifications

Specifications

SIN3B
Monoclonal
0.2-1.0 mg/mL
PBS with no preservative; pH 7.4
O75182
SIN3 homolog B, transcription regulator, SIN3 homolog B, transcriptional regulator, histone deacetylase complex subunit Sin3b, paired amphipathic helix protein Sin3b, transcriptional corepressor Sin3b
Mouse
IgG2a, kappa
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
23309
ELISA
2C11
Unconjugated
SIN3B
Liquid
SIN3B
SIN3B (NP_056075.1, 1063 a.a. ∽ 1160 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Documents
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