SIN3B Mouse anti-Human, Clone: 2C11, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA521444
Peptide Sequence: HKMVFIVNSE DYMYRRGTLC RAKQVQPLVL LRHHQHFEEW HSRWLEDNVT VEAASLVQDW LMGEEDEDMV PCKTLCETVH VHGLPVTRYR VQYSRRPAActs as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.
|PBS with no preservative; pH 7.4|
|SIN3 homolog B, transcription regulator, SIN3 homolog B, transcriptional regulator, histone deacetylase complex subunit Sin3b, paired amphipathic helix protein Sin3b, transcriptional corepressor Sin3b|
|-20° C, Avoid Freeze/Thaw Cycles|
|SIN3B (NP_056075.1, 1063 a.a. ∽ 1160 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.|
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