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SIRT5 Chicken anti-Human, Mouse, Polyclonal, Invitrogen™

Chicken Polyclonal Antibody

Manufacturer:  Invitrogen PA520966

Catalog No. PIPA520966


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Description

Description

A suggested positive control is human liver tissue lysate. PA5-20966 can be used with blocking peptide PEP-1080.

The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT5 localizes to mitochondria, deacetylates carbamoyl phosphate synthetase 1, and is involved in the regulation of the urea cycle.
Specifications

Specifications

SIRT5
Polyclonal
Unconjugated
SIRT5
Liquid
SIRT5
A 17 amino acid peptide near the carboxy terminus of human SIRT5.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q9NXA8, Q8K2C6
SIR2L5; NAD-dependent deacetylase sirtuin-5; SIR2-like protein 5; silent mating type information regulation 2, S.cerevisiae, homolog 5; sir2-like 5; sirtuin type 5
Chicken
IgY
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
23408, 68346
Documents
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