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SIRT6 Chicken anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Chicken Polyclonal Antibody

Manufacturer:  Invitrogen PA520967

Catalog No. PIPA520967


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Description

Description

A suggested positive control is Hela cell lysate. PA5-20967 can be used with blocking peptide PEP-1081.

The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT6 is a histone H3 lysine 9 deacetylase and is thought to stabilize the DNA-dependent protein kinase at double-stranded DNA breaks and may have a role in the process of mammalian aging.
Specifications

Specifications

SIRT6
Polyclonal
Unconjugated
SIRT6
Liquid
SIRT6
A 17 amino acid peptide near the carboxy terminus of human SIRT6.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q8N6T7, P59941
SIR2L6; NAD-dependent deacetylase sirtuin-6; SIR2-like protein 6; sir2-related protein type 6; sirtuin type 6
Chicken
IgY
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
299638, 50721, 51548
Documents
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