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SIT Mouse anti-Human, PE, Clone: SIT-01, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA119652

Catalog No. 01-676-379


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Description

Description

SIT (SHP2-interacting transmembrane adaptor protein) is expressed exclusively in lymphoid organs and acts either as a positive or as a negative regulatory element in T cell activation and in T cell development. Binding to Grb2 plays a pivotal role in signal transduction. Hubener et al. (2001) determined that the SIT gene contains 5 exons and spans 1.8 kb of genomic DNA. The SIT promoter demonstrated strong transcriptional activity and potential binding sites for both ubiquitous and lymphoid-specific transcription factors.
Specifications

Specifications

SIT
Monoclonal
0.1 mg/mL
PBS with 0.2% BSA and 15mM sodium azide
Q9Y3P8
MGC125908, MGC125909, MGC125910, RP11-331F9.5, SIT
Mouse
IgG1
100 μg
4° C, store in dark, DO NOT FREEZE!
Primary
27240
Flow Cytometry
SIT-01
PE
SIT1
Liquid
SIT1
Bacterially produced recombit intracellular fragment of human SIT.
Purified
RUO
Antibody
Monoclonal
Human
Documents
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