CD150 Mouse anti-Human, Clone: IPO-3, Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA17626
MA1-7626 detects SLAM from human samples. MA1-7626 has been successfully used in ELISA, flow cytometry, Immunohistochemistry and Immunoprecipitation procedures. The MA1-7626 immunogen is an activated B cell line. Store at 4°C short term. For long term storage, store at -80°C.CD150 (SLAM, Signaling Lymphocyte Activation Molecule) belongs to the immunoglobulin gene superfamily, and is involved in T cell stimulation. SLAM is constitutively expressed on peripheral blood memory T cells, T cell clones, immature thymocytes, and a proportion of B cells, and is rapidly induced on naive T cells after activation. Activated B cells express the membrane bound form, the soluble form and the cytoplasmic isoforms of SLAM. It is suggested that signalling through homophilic SLAM-SLAM binding during B to B and B to T cell interactions enhances the expansion and differentiation of activated B cells. Reports suggest that the extracellular domain of CD150 is the receptor for the measles virus and acts as a co-activator on T cells and B cells. Moreover, CD150 is thought to interact with SH2D1A and with PTPN11 via its cytoplasmic domain. Mutations CD150 gene may be associated with X-linked lympho-proliferative disease (XLP).
|PBS with no preservative; pH 7.2|
|CD150, CDw150, SLAM, IPO-3, signaling lymphocytic activation molecule, SLAMF1|
|4°C or -80°C if preferred|
|ELISA, Flow Cytometry, Immunohistochemistry, Immunoprecipitation|
|Activated B cell line.|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok