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CRACC Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA525589

Catalog No. PIPA525589


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Description

Description

SLAMF7 contains one Ig-like C2-type (immunoglobulin-like) domain. Isoform 1 mediates NK cell activation through a SAP-independent extracellular signal-regulated ERK-mediated pathway. It may play a role in lymphocyte adhesion. Isoform 3 does not mediate any activation. SAP can bind the cytoplasmic tail of isoform 1 when phosphorylated in the presence of Fyn (in vitro). SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Expression was detected in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-, or T-cell lines. The isoform 3 is expressed at much lower level than isoform 1. There are three named isoforms.
Specifications

Specifications

CRACC
Polyclonal
PBS with 0.09% sodium azide
Q9NQ25
SLAMF7, CD319, CRACC, CS1, 19A24 protein, CD2 subset 1, CD2-like receptor activating cytotoxic cells, CD2-like receptor-activating cytotoxic cells, membrane protein FOAP-12, novel LY9 lymphocyte antigen 9 like protein, protein 19A
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
57823
Western Blot
Unconjugated
SLAMF7
Liquid
SLAMF7
KLH conjugated synthetic peptide between 58-85 amino acids from the central region of human SLAMF7
Protein A, Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
Documents
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