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SLC22A17 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520543

Catalog No. PIPA520543


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Description

Description

A suggested positive control is SK-N-SH cell lysate. PA5-20543 can be used with blocking peptide PEP-0663.

The Slc22 family of organic anion and cation transporters (OATs, OCTs, OCTNs) are transmembrane proteins expressed predomitly in kidney and liver. Each contain 12 predicted alpha-helical transmembrane domains (TMDs) and one large extracellular loop between TMDs 1 and 2. Transporters of the SLC22 family function in different ways such as uniporters that mediate facilitated diffusion in either direction (OCTs), as anion exchangers (OAT1, OAT3 and URAT1), and as Na(+)/l-carnitine cotransporter (OCTN2). Slc22 family members participate in the absorption and/or excretion of drugs, xenobiotics, and endogenous compounds in intestine, liver, and kidney, and perform homeostatic functions in brain and heart. Mutations in the Slc22 family may cause specific diseases such as primary systemic carnitine deficiency or idiopathic renal hypouricemia and may change drug absorption or excretion. Recent studies show the expression of Slc22A17 as receptor for Lipocalin 2 is relatively high in hematopoietic stem cells.
Specifications

Specifications

Slc22A17
Polyclonal
Unconjugated
SLC22A17
Liquid
SLC22A17
A 14 amino acid peptide near the carboxy terminus of the human Slc22A17.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q8WUG5, Q9D9E0, Q9P290
24p3R, BOCT, BOIT, NGALR, NGALR2, NGALR3, hBOIT; 24p3 receptor; NGAL receptor; brain-type organic cation transporter; lipocalin-2 receptor; neutrophil gelatinase-associated lipocalin receptor; potent brain type organic ion transporter; solute carrier family 22 (organic cation transporter), member 17; solute carrier family 22 member 17
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
305886, 51310, 59049
Documents
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