SLC4A8 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA527880
PA5-27880 targets SLC4A8 in WB applications and shows reactivity with Human samples. The PA5-27880 immunogen is recombit fragment corresponding to a region within amino acids 1 and 295 of Human SLC4A8. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.Mediates electroneutral sodium- and carbonate-dependent choride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity.
|Recombit fragment corresponding to a region within amino acids 1 and 295 of Human SLC4A8|
|Antigen affinity chromatography|
|0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7|
|NBC3, NDCBE, Na+-driven Cl-HCO3 exchanger, electroneutral Na(+)-driven Cl-HCO3 exchanger, electroneutral sodium bicarbonate exchanger 1, k-NBC3, solute carrier family 4 member 8|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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