SLUG Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA186737
In Western blot, this antibody detects a band at ~30kDa in 293 cell lysate. Rabbit anti Slug antibody detects Slug, a member of the Snail family of zinc finger transcription factors, whose expression is induced by FGF, BMP, and TGF-beta.This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects.
|13 amino acid peptide sequence near the centre of human Slug|
|Immunofluorescence, Western Blot|
|PBS with 0.02% sodium azide|
|MGC10182, SLUG, SLUGH1, WS2D|
|4°C or -20°C if preferred|
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