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SMAD7 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA141506

Catalog No. 01-675-331


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Description

Description

This antibody is predicted to react with chimpanzee, canine, pufferfish, xenopus and zebrafish based on sequence homology. Suggested positive control: A549, HepG2.

SMADs are members of the MAD-related family of molecules. MAD-related proteins are a  family of intracellular proteins that are essential components in the signaling pathways of the serine/threonine kinase receptors of the transforming growth factor beta superfamily.  SMADs can be divided into receptor-regulated SMADs (R-SMADs: SMAD1, SMAD2, SMAD5, SMAD8 and SMAD9), common-mediator SMAD (co-SMAD: SMAD4), and inhibitory SMADs (I-SMADs: SMAD6 and SMAD7).  SMAD1, SMAD5, SMAD8 and SMAD9 have high degrees of homology and antibodies are available that recognize sequences common to all of them.  SMAD8 and SMAD9 are typically used as alternate names for one another in the literature. 
Specifications

Specifications

SMAD7
Polyclonal
Unconjugated
SMAD7
Liquid
SMAD7
Synthetic peptides corresponding to residues R(12) L W R S R A P G G E D E E E G A G(29) and E(36) L R G E G A T D S R A H G A(50) of human SMAD7.
Protein G
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Western Blot
1.0 mg/mL
PBS with no preservative
O15105, O35253, O88406
CRCS3, FLJ16482, MADH7, MADH8
Rabbit
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
17131, 4092, 81516
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