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SMARCA2, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA125448

Catalog No. PIPA125448

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
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Description

Description

The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Two transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism.

PA1-25448 detects SMARCA2 from human samples. PA1-25448 is expected to cross react with mouse (100% conserved), rat (100% conserved), Xenopus laevis (88% conserved), zebrafish (87% conserved), and chicken (94% conserved) due to sequence homology.PA1-25448 has been successfully used in Western blot procedures.The PA1-25448 immunogen is a synthetic peptide, conjugated to maleimide-activated KLH, corresponding to residues K(1354) E D V E K A K K R R G R P P A E(1370) of SMARCA2, with an N-terminal added cysteine.
Specifications

Specifications

SMARCA2
Polyclonal
Unconjugated
SMARCA2
Purified
SMARCA2, smarca2.L
Synthetic peptide, conjugated to maleimide-activated KLH, corresponding to residues K(1354) E D V E K A K K R R G R P P A E(1370) of SMARCA2, with an
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Fish, Human, Murine, Rat, Xenopus laevis, Zebrafish
Immunocytochemistry, Immunofluorescence, Western Blot
1.3mg/mL
PBS with 15mM sodium azide; pH 7.4
P51531, Q6DIC0
BAF190, BRM, FLJ36757, MGC74511, SNF2, SNF2L2, SNF2LA, SWI2, Sth1p, hBRM, hSNF2a
Rabbit
IgG
100μL
Store at -20°C
Primary
6595
Documents
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