Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

SMC1 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA529691

Catalog No. PIPA529691


Add to cart

Description

Description

PA5-29691 targets SMC1A in IHC (P) and WB applications and shows reactivity with Human and mouse samples. The PA5-29691 immunogen is recombit fragment corresponding to a region within amino acids 308 and 546 of Human SMC1A. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintece of chromosomes (SMC) proteins, SMC3 and either SMC1L2 or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation.
Specifications

Specifications

SMC1
Polyclonal
Unconjugated
SMC1A
Liquid
SMC1A
Recombit fragment corresponding to a region within amino acids 308 and 546 of Human SMC1A
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
1 mg/mL
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Q14683, Q9CU62
CDLS2, DXS423E, SB1.8, SMC1, SMC1L1, SMC1alpha, SMCB, SMC protein 1A, SMC-1-alpha, SMC-1A, SMC1 (structural maintece of chromosomes 1, yeast)-like 1, SMC1 structural maintece of chromosomes 1-like 1, segregation of mitotic chromosomes 1, structural maintece of chromosomes protein 1A
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
24061, 8243
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit