SMC2 Mouse anti-Human, Clone: E1M, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA112643
A suggested positive control for this product is HeLa cells.CAP-E and CAP-C (Chromosome Associated Protein-E & C) are also SMC (Structural Maintece of Chromosome) family members that form a heterodimeric complex required for mitotic chromosome condensation to achieve proper segregation of genetic information during subsequent cell division. hCAP-C/hCAP-E is a component of a multiprotein complex called condensin that interacts with phosphorylation of Histone H3 resulting in the mitotic chromosome condensation. The distribution patterns of the two heterodimeric complexes in interphase nucleus indicate independent behavior of the two complexes during cell cycle. These results suggest that the two distinct complexes are involved in different aspects of mitotic chromosome organization in humar cells.
|PBS with 0.08% sodium azide|
|SMC2L1, CAPE, hCAP-E|
|-20° C, Avoid Freeze/Thaw Cycles|
|Recombit protein corresponding to aa 523-768 of human CAP-E.|
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