SNAIL Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA523472
DescriptionZinc finger protein SNAI1 (SNAIL)is a zinc finger transcriptional repressor which down regulates the expression of the ectodermal gene within the mesoderm and functions to form the mesoderm and neural crest. It is reported that SNAI1 acts as an important factor of tumor invasion as evidenced by its role in E-cadherin down-regulation and induction of epithelial-mesenchymal transition (EMT). In human breast cancer, the expression of SNAI1 and/or the homologous SNAI2 (Slug) has been associated with E-cadherin repression, local or distant metastasis, tumor recurrence, or poor prognosis in different tumor series. It is also reported that Snail 1 protein in the stromamay be anew putative prognosis marker for colon tumors.
|Synthetic peptide (87 ELTSLSDEDSGKGSQPPS 104) of SNAI1/Snail protein.|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|PBS with 0.05% sodium azide|
|SLUGH2, SNA, SNAH, SNAIL, SNAIL1, dJ710H13.1, protein sna, protein snail homolog 1, snail 1 homolog, snail 1 zinc finger protein, snail 1, zinc finger protein, zinc finger protein SNAI1|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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