SNAP alpha/beta Mouse anti-Bovine, Chicken, Human, Rat, Clone: 16D1, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA112451
A suggested positive control for this product is rat brain lysate.SNAPs (soluble NSF attachment proteins), acting in concert with SNAREs ( SNAP receptors) and the N-ethylmaleimide-sensitive fusion protein (NSF) are required for the fusion of transport vesicles to their target membranes in synaptic transmission, intra-Golgi transport, endosome-toendosome fusion and transcytotic vesicles-to-plasma membrane transport. Vesicle-to-target membrane docking (initial contact) occurs when the vesicle SNARE binds to its cognate target membrane SNARE. a-SNAP (or b-SNAP in brain) then binds to this docking complex and mediates the binding of NSF and thus the formation of a 20S fusion particle. It is thought that, once NSF is bound, ATP hydrolysis by NSF initiates the fusion process.
|PBS with 50% glycerol and no preservative; pH 7.5|
|P81125, Q17QQ3, P60878, P54920, P60880, P54921, P60881|
|NAPA, SNAP25, Synaptosomal-Associated Protein alpha/beta|
|-20° C, Avoid Freeze/Thaw Cycles|
|100858304, 140673, 25012, 396444, 518407, 540853, 6616, 8775|
|Recombit human alpha SNAP.|
|Bovine, Chicken, Human, Rat|
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