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SNAP alpha Mouse anti-Bovine, Human, Rat, Clone: 15D4, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA112453

Catalog No. 01-674-320


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Description

Description

SNAPs (solubleNSFattachment proteins), acting in concert with SNAREs ( S N A P r e c eptors) and the N - ethylmaleimide- s e nsitive f u sion protein (NSF) are required for the fusion of transport vesicles to their target membranes in synaptic transmission, intra-Golgi transport, endosome-toendosome fusion and transcytotic vesicles-to-plasma membrane transport. Vesicle-to-target membrane docking (initial contact) occurs when the vesicle SNARE binds to its cognate target membrane SNARE. a-SNAP (or b-SNAP in brain) then binds to this docking complex and mediates the binding of NSF and thus the formation of a 20S fusion particle. It is thought that, once NSF is bound, ATP hydrolysis by NSF initiates the fusion process.
Specifications

Specifications

SNAP alpha
Monoclonal
Unconjugated
NAPA
Liquid
NAPA
Recombit human alpha-SNAP
Affinity chromatography
RUO
Antibody
Monoclonal
Bovine, Human, Rat
ELISA, Immunoprecipitation, Western Blot
15D4
PBS with 50% glycerol and no preservative; pH 7.5
P81125, P54920, P54921
Synaptosomal-Associated Protein alpha
Mouse
IgG1
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
140673, 518407, 8775
Documents
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