SNAP alpha Mouse anti-Bovine, Human, Rat, Clone: 4E4, Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA112452
A suggested positive control for this product is rat brain lysate.SNAPs (solubleNSFattachment proteins), acting in concert with SNAREs ( S N A P r e c eptors) and the N - ethylmaleimide- s e nsitive f u sion protein (NSF) are required for the fusion of transport vesicles to their target membranes in synaptic transmission, intra-Golgi transport, endosome-toendosome fusion and transcytotic vesicles-to-plasma membrane transport. Vesicle-to-target membrane docking (initial contact) occurs when the vesicle SNARE binds to its cognate target membrane SNARE. a-SNAP (or b-SNAP in brain) then binds to this docking complex and mediates the binding of NSF and thus the formation of a 20S fusion particle. It is thought that, once NSF is bound, ATP hydrolysis by NSF initiates the fusion process.
|Human a-SNAP protein.|
|Bovine, Human, Rat|
|Immunoprecipitation, Western Blot|
|PBS with 50% glycerol and no preservative; pH 7.5|
|P81125, P54920, P54921|
|Synaptosomal-Associated Protein alpha|
|-20° C, Avoid Freeze/Thaw Cycles|
|140673, 518407, 8775|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok