SOCS3 Mouse anti-Human, Clone: SO1, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA119373
DescriptionSOCS3 (suppressor of cytokine signaling 3), also known as CIS3 (cytokine-inducible SH2 protein 3) is a negative regulator of particular cytokine signaling pathways. SOCS3 is induced by a variety of cytokines and other stimuli, such as erythropoietin, leptin and lipopolysaccharides and inhibits tyrosinkinase activity of JAK kinases, or e.g. JNK phosphorylation. SOCS3 modulates cytokine-mediated and neoplastic-proliferative responses and is involved also in maintaining leukocytes in quiescent state until antigen stimulation.
|PBS with 15mM sodium azide; pH 7.4|
|Suppressor of cytokine signaling|
|4° C, do not freeze|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|Full-length SOCS3 protein.|
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