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SOCS3 Mouse anti-Human, Clone: SO1, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA119373

Catalog No. 01-676-129


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Description

Description

SOCS3 (suppressor of cytokine signaling 3), also known as CIS3 (cytokine-inducible SH2 protein 3) is a negative regulator of particular cytokine signaling pathways. SOCS3 is induced by a variety of cytokines and other stimuli, such as erythropoietin, leptin and lipopolysaccharides and inhibits tyrosinkinase activity of JAK kinases, or e.g. JNK phosphorylation. SOCS3 modulates cytokine-mediated and neoplastic-proliferative responses and is involved also in maintaining leukocytes in quiescent state until antigen stimulation.
Specifications

Specifications

SOCS3
Monoclonal
1 mg/mL
PBS with 15mM sodium azide; pH 7.4
O14543
Suppressor of cytokine signaling
Mouse
IgG2b
100 μg
4° C, do not freeze
Primary
9021
Immunocytochemistry, Immunofluorescence, Western Blot
SO1
Unconjugated
SOCS3
Liquid
SOCS3
Full-length SOCS3 protein.
Purified
RUO
Antibody
Monoclonal
Human
Documents
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