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SOCS3 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA528098

Catalog No. PIPA528098


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Description

Description

PA5-28098 targets SOCS3 in IHC (P) and WB applications and shows reactivity with Human samples. The PA5-28098 immunogen is synthetic peptide corresponding to a region within amino acids 163 and 225 of Human SOCS3. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.
Specifications

Specifications

SOCS3
Polyclonal
Unconjugated
SOCS3
Liquid
SOCS3
Synthetic peptide corresponding to a region within amino acids 163 and 225 of Human SOCS3
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 40% glycerol and 0.01% thimerosal; pH 7
O14543
ATOD4, CIS3, Cish3, SOCS-3, SSI-3, SSI3, CIS-3, STAT-induced STAT inhibitor 3, cytokine-induced SH2 protein 3, cytokine-inducible SH2 protein 3
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
9021
Documents
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