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SOX17 Rabbit anti-Human, Marsupial, Mouse, Non-human primate, Rat, Zebrafish, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523352

Catalog No. PIPA523352

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
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Description

Description

SOX17, also known as transcription factor SOX-17, as the name suggests is a transcription factor or a probable transcriptional activator in the premeiotic germ cells. It belongs to the SRY-related HMG box family of transcription factors with a high-mobility group DNA-binding domain (HMG box), that plays a key role in embryogenesis and binds to the sequences 5 ft.-AACAAT- ft.3 or 5 ft.-AACAAAG-3 ft.. SOX17 plays an essential role in cardiac mesoderm specification as well as in definitive hematopoiesis, maintaining fetal hematopoietic stem cells, hematopoiesis in the fetal liver and yolk sac. Along with beta-catenin, it is known to cooperate in the regulation of transcription of endodermal genes. Defects in SOX17 are known to cause a severe defects in fetal hematopoiesis. 
Specifications

Specifications

SOX17
Polyclonal
Unconjugated
SOX17
Liquid
SOX17
Synthetic peptide (80 KDERKRLAQQNPDLHNAEL 98) of SOX17 protein.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Marsupial, Mouse, Non-human primate, Rat, Zebrafish
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 0.05% sodium azide
Q9H6I2, Q61473
VUR3, SRY-related HMG-box transcription factor SOX17, transcription factor SOX-17
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
20671, 30544, 312936, 64321
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