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SOX17 Rabbit anti-Chicken, Human, Marsupial, Mouse, Non-human primate, Porcine, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523382

Catalog No. PIPA523382


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Description

Description

SOX17, also known as Transcription factor SOX-17, is, as the name suggests, a transcription factor and a probable transcriptional activator in the premeiotic germ cells. It belongs to the SRY-related HMG box family of transcription factors with a high-mobility group DNA-binding domain (HMG box) that plays a key role in embryogenesis and binds to the sequences 5 ft.-AACAAT- ft.3 or 5 ft.-AACAAAG-3 ft.. SOX17 plays an essential role in cardiac mesoderm specification as well as in definitive hematopoiesis, maintaining fetal hematopoietic stem cells, hematopoiesis in the fetal liver and yolk sac. Along with beta-catenin it is known to cooperate in the regulation of transcription of endodermal genes. Defects in SOX17 are known to cause a severe defect in fetal hematopoiesis.
Specifications

Specifications

SOX17
Polyclonal
Unconjugated
SOX17
Liquid
SOX17
Synthetic peptide (131 DHPNYKYRPRRRKQVKRLK 149) of SOX17 protein.
Protein A
RUO
Antibody
Polyclonal
Chicken, Human, Marsupial, Mouse, Non-human primate, Porcine
Western Blot
0.5 mg/mL
PBS with 0.05% BSA and 0.05% sodium azide
Q9H6I2, Q61473
VUR3, SRY-related HMG-box transcription factor SOX17, transcription factor SOX-17
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
100154087, 20671, 428534, 64321
Documents
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