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SP1 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA529165

Catalog No. PIPA529165


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Description

Description

PA5-29165 targets SP1 in IHC (P), IP and WB applications and shows reactivity with Human and mouse samples. The PA5-29165 immunogen is recombit fragment corresponding to a region within amino acids 18 and 303 of Human SP1. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.
Specifications

Specifications

SP1
Polyclonal
Unconjugated
SP1
Liquid
SP1
Recombit fragment corresponding to a region within amino acids 18 and 303 of Human SP1
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
ChIP assay, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
0.06 mg/mL
PBS with 1% BSA, 20% glycerol and 0.025% Proclin 300; pH 7
P08047, O89090
specificity protein 1, transcription factor Sp1
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
20683, 6667
Documents
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