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SPG21 Mouse anti-Human, Clone: 2B11, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA521907

Catalog No. PIMA521907


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Description

Description

Peptide Sequence: PHKIRDIPVT IMDVFDQSAL STEAKEEMYK LYPNARRAHL KTGGNFPYLC RSAEVNLYVQ IHLLQFHGTK YAAIDPSMVS AEELEVQKGS LGISQE

The protein encoded by this gene was identified by a two-hybrid screen using CD4 as the bait. It binds to the hydrophobic C-terminal amino acids of CD4 which are involved in repression of T cell activation. The interaction with CD4 is mediated by the noncatalytic alpha/beta hydrolase fold domain of this protein. It is thus proposed that this gene product modulates the stimulatory activity of CD4. At least three different transcript variants encoding two different isoforms have been found for this gene.
Specifications

Specifications

SPG21
Monoclonal
0.2-1.0 mg/mL
PBS with no preservative; pH 7.4
Q9NZD8
Spastic paraplegia 21 (autosomal recessive, Mast syndrome), ACP33, BM-019, GL010, MASPARDIN, MAST
Mouse
IgG2a, kappa
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
51324
ELISA
2B11
Unconjugated
SPG21
Liquid
SPG21
SPG21 (NP_057714, 211 a.a. ∽ 306 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Documents
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