SPG21 Mouse anti-Human, Clone: 2B11, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA521907
Peptide Sequence: PHKIRDIPVT IMDVFDQSAL STEAKEEMYK LYPNARRAHL KTGGNFPYLC RSAEVNLYVQ IHLLQFHGTK YAAIDPSMVS AEELEVQKGS LGISQEThe protein encoded by this gene was identified by a two-hybrid screen using CD4 as the bait. It binds to the hydrophobic C-terminal amino acids of CD4 which are involved in repression of T cell activation. The interaction with CD4 is mediated by the noncatalytic alpha/beta hydrolase fold domain of this protein. It is thus proposed that this gene product modulates the stimulatory activity of CD4. At least three different transcript variants encoding two different isoforms have been found for this gene.
|PBS with no preservative; pH 7.4|
|Spastic paraplegia 21 (autosomal recessive, Mast syndrome), ACP33, BM-019, GL010, MASPARDIN, MAST|
|-20° C, Avoid Freeze/Thaw Cycles|
|SPG21 (NP_057714, 211 a.a. ∽ 306 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.|
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