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SGPP1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA112723

Catalog No. PIPA112723


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Description

Description

A suggested positive control for this product is human brain lysate.

Sphingosine 1-phosphate (S1P) is a highly bioactive lipid that has a myriad of biological effects both intracellularly as a second messenger and extracellularly by binding to the S1P(1-5)/G-protein-coupled receptors of the endothelial differentiation gene family. Intracellularly, at least two enzymes, sphingosine kinase (1 and 2) and S1P phosphatase, regulate the activity of S1P by governing the phosphorylation of S1P. Regulation of hS1Pase1 with the resultant changes in cellular and secreted S1P has important implications in cell proliferation, angiogenesis and apoptosis.
Specifications

Specifications

SGPP1
Polyclonal
PBS with 0.08% sodium azide
Q9BX95
SPPase1
Rabbit
IgG
10 Miniblots
-20° C, Avoid Freeze/Thaw Cycles
Primary
81537
Western Blot
Unconjugated
SGPP1
Liquid
SGPP1
Synthetic peptide corresponding to sphingosine 1-phosphate phosphatase 1.
Ammonium sulfate precipitation
RUO
Antibody
Polyclonal
Human
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