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SGPP1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA112723

Catalog No. PIPA112723

Item Discontinued This item has been discontinued by the supplier and is no longer available. Please reach out to your sales representative.


Description

Description

A suggested positive control for this product is human brain lysate.

Sphingosine 1-phosphate (S1P) is a highly bioactive lipid that has a myriad of biological effects both intracellularly as a second messenger and extracellularly by binding to the S1P(1-5)/G-protein-coupled receptors of the endothelial differentiation gene family. Intracellularly, at least two enzymes, sphingosine kinase (1 and 2) and S1P phosphatase, regulate the activity of S1P by governing the phosphorylation of S1P. Regulation of hS1Pase1 with the resultant changes in cellular and secreted S1P has important implications in cell proliferation, angiogenesis and apoptosis.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

SGPP1
Polyclonal
SGPP1
SPPase1
Rabbit
Ammonium sulfate precipitation
RUO
81537
-20° C, Avoid Freeze/Thaw Cycles
Liquid
Western Blot
Unconjugated
Q9BX95
SGPP1
Synthetic peptide corresponding to sphingosine 1-phosphate phosphatase 1.
10 Miniblots
Primary
Human
Antibody
IgG
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