SGPL1 Rabbit anti-Bovine, Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA112722
By Western blot, PA1-12722 detects a ~64 kDa protein representing S1P lyase 1 from MDBK cell lysate.Sphingosine-1-phosphate lyase cleaves phosphorylated sphingoid bases, such as sphingosine-1 phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis. The catalytic activity of sphingosine 1- phosphate lyase converts sphingosine 1-phosphate to phosphoethanolamine and palmitaldehyde using Pyridoxal phosphate as a co-factor. Sphingosine 1-phosphate lyase is a type III membrane protein found in the endoplasmic reticulum. Sphingosine 1-phosphate lyase is found primarily in the liver and kidney. Sphingosine 1-phosphate lyase belongs to the group II decarboxylase family.
|PBS with 0.08% sodium azide|
|O95470, Q8R0X7, Q8CHN6|
|AI428538, D10Xrf456, Spl|
|-20° C, Avoid Freeze/Thaw Cycles|
|20397, 286896, 522515, 8879|
|Synthetic peptide corresponding to sphingosine 1-phosphate lyase 1.|
|Antigen affinity chromatography|
|Bovine, Human, Mouse, Rat|
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