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SPHK1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA526261

Catalog No. PIPA526261


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Description

Description

SPHK1 is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974). Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430) and serum.
Specifications

Specifications

SPHK1
Polyclonal
PBS with 0.09% sodium azide
Q9NYA1
SPHK, SK 1, SPK 1
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
8877
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
SPHK1
Liquid
SPHK1
KLH conjugated synthetic peptide between 313-343 amino acids from the C-terminal region of human SPHK1
Ammonium sulfate precipitation, Size-exclusion - Dialysis
RUO
Antibody
Polyclonal
Human
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