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SPIB Rabbit anti-Bovine, Canine, Equine, Human, Mouse, Non-human primate, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523501

Catalog No. PIPA523501


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Description

Description

Transcription factor Spi-B belongs to the ETS family and contains one ETS DNA-binding domain. Spi-B inhibits human plasma cell differentiation by repressing BLIMP1 and XBP-1 expression, thus maintains activity of germinal center and memory B cells by direct repression of major plasma cell factors and thereby plasma cell differentiation. It is reported that Spi-B regulates Progressive multifocal leukoencephalopathy (PML) causing JCVirus gene expression, and may play an important role in JCV activity in the immune and nervous systems. It is also reported Spi-B is expressed in various murine and hematopoietic lines except T lymphoid lines.
Specifications

Specifications

SPIB
Polyclonal
Unconjugated
SPIB
Liquid
SPIB
Synthetic peptide (23 FYDLDSCKHSSYPDSEGA 40) of Spi-B protein.
Protein A
RUO
Antibody
Polyclonal
Bovine, Canine, Equine, Human, Mouse, Non-human primate
Western Blot
0.5 mg/mL
PBS with 0.05% BSA and 0.05% sodium azide
Q01892, O35906
SPI-B, transcription factor Spi-B
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
100688036, 102150831, 272382, 6689, 784460
Documents
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