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SR-BI Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA131405

Catalog No. PIPA131405


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Description

Description

PA1-31405 detects SR-BI from rat, mouse, human samples. PA1-31405 has been successfully used in immunoprecipitation, immunohistochemistry (paraffin tissue), Western blot applications. The PA1-31405 immunogen is: A C-terminal peptide containing residues from mouse Scavenger Receptor-BI (within residues 450-509).

High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. The SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester. SR-BI binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidogenic tissues, and mediates selective cholesterol uptake by a distinct mechanism. In mice, it seems that SR-BI plays a key role in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland.
Specifications

Specifications

SR-BI
Polyclonal
Unconjugated
SCARB1
Liquid
SCARB1
A C-terminal peptide containing residues from mouse Scavenger Receptor-BI (within residues 450-509).
IgG fraction
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
1.0 mg/mL
PBS with 0.1% sodium azide; pH 7-8
Q8WTV0, Q61009, P97943
SCARB1, SR-B1, SR-BI, Scavenger Receptor-BI, Scavenger Receptor-B1
Rabbit
IgG
100 μL
4° C, do not freeze
Primary
20778, 25073, 949
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