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CD254 (RANK Ligand) Goat anti-Mouse, Polyclonal, Invitrogen™

Goat Polyclonal Antibody

Manufacturer:  Invitrogen PA120150

Catalog No. PIPA120150


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Description

Description

PA1-20150 detects sRANKL in mouse samples. PA1-20150 has been successfully used in ELISA and Western blot procedures. The PA1-20150 immunogen is recombit, full length, mouse sRANKL. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

TRANCE, also called RANKL (RANK ligand), OPGL (Osteoprotegrin ligand), and ODF (Osteoclast differentiation factor), is a type II transmembrane signaling protein of the TNF superfamily. The extracellular domain contains two potential N-linked glycosylation sites. Mouse TRANCE cDNA encodes a 316 amino acid protein with a calculated molecular mass of approximately 28 kDa. As a result of glycosylation, recombit mouse TRANCE migrates as an approximately 36 kDa protein in SDS-PAGE. Human and mouse TRANCE share approximately 85% amino acid sequence identity. TRANCE was originally identified as an immediate early gene upregulated by T cell receptor stimulation. It is a key regulator of the immune system and of bone development and homeostasis.
Specifications

Specifications

CD254 (RANK Ligand)
Polyclonal
Unconjugated
Tnfsf11
Liquid
TNFSF11
Recombit, full length, mouse sRANKL.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Mouse
ELISA, Neutralization, Western Blot
1 mg/mL
PBS with no preservative; pH 7.4
O35235
Ly109l, ODF, OPG, OPGL, RANKL, Trance
Goat
IgG
50 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
21943
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