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SRPX2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520844

Catalog No. PIPA520844


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Description

Description

A suggested positive control is human lung tissue lysate. PA5-20844 can be used with blocking peptide PEP-0958.

Sushi-repeat-containing protein X-linked 2 (SRPX2) is a neural gene functioning in the speech and language center of the human brain; mutations in this gene lead to epilepsy, speech dyspraxia, mental retardation and cognitive disorders. Recently, SRPX2 was found to be a novel mediator of angiogenesis and can act as a ligand for the urokinase-type plasminogen activator, a protein that can facilitate invasive migration of sprouting endothelial cells. SRPX2 is also overexpressed in gastric cancer, leading to increased phosphorylation levels of focal adhesion kinase and enhanced cellular migration and adhesion, suggesting that SRPX2 may be a potential target in the treatment of metastatic cancers.
Specifications

Specifications

SRPX2
Polyclonal
Unconjugated
SRPX2
Liquid
SRPX2
A 16 amino acid peptide from near the amino terminus of human SRPX2.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
O60687, Q8R054, B5DF94
RP11-524D16__A.1, BPP, CBPS, PMGX, RESDX, SRPUL; sushi repeat-containing protein SRPX2; sushi-repeat protein up-regulated in leukemia; sushi-repeat-containing protein, X-linked 2
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
27286, 317181, 68792
Documents
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