SSRP1 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA112699
DescriptionStructure specific recognition protein 1 (SSRP1). The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63.
|PBS with 0.08% sodium azide|
|Structure specific recognition protein 1|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunoprecipitation, Western Blot|
|Recombit protein corresponding to residues 1-242 of human SSRP1 .|
|Ammonium sulfate precipitation|
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