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synovial sarcoma, X breakpoint 2 (B02), Mouse anti-Human, Polyclonal Antibody, Abnova™

Mouse polyclonal antibody raised against a full-length human SSX2 protein.

Manufacturer:  Abnova Corporation H00006757B02

Catalog No. 89-006-285


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Description

Description

The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq

Sequence: MNGDDAFARRPTVGAQIPEKIQKAFDDIAKYFSKEEWEKMKASEKIFYVYMKRKYEAMTKLGFKATLPPFMCNKRAEDFQGNDLDNDPNRGNQVERPQMTFGRLQGISPKIMPKKPAEEGNDSEEVPEASGPQNDGKELCPPGKPTTSEKIHERSGPKRGEHAWTHRLRERKQLVIYEEISDPEEDDE
Specifications

Specifications

synovial sarcoma, X breakpoint 2
Unconjugated
No additive
BC016957
HD21|HOM-MEL-40|MGC119055|MGC15364|MGC3884|SSX
Mouse
50 uL
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Primary
6757
Western Blot
Mouse polyclonal antibody raised against a full-length human SSX2 protein.
SSX2
Serum
SSX2
SSX2 (AAH16957, 1 a.a. ~ 188 a.a) full-length human protein.
RUO
Y
Polyclonal
Human
Documents
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