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ST3GAL6 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520748

Catalog No. PIPA520748


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Description

Description

A suggested positive control is Hela cell lysate. PA5-20748 can be used with blocking peptide PEP-0862.

Sialyltransferases catalyze the transfer of sialic acid from cytidine 5-prime monophospho-N-acetylneuraminic acid (CMP-NeuAc) to terminal positions of glycoprotein and glycolipid carbohydrate groups. Terminal NeuAc residues are key determits of carbohydrate structures, such as the sialyl-Lewis X determits, and are widely distributed in many cell types. However, cancer cells often express more heavily sialylated glycans on their cell surface and this feature sometimes correlates with invasiveness. In contrast, expression of ST3gal6, a member of the sialyltransferase family that sialylates type II lactosamine structures on glycoproteins and glycolipids, was found to be significantly decreased by hypermethylation of the gene in gastrointestinal cancer. At least three isoforms of ST3gal6 are known to exist.
Specifications

Specifications

ST3gal6
Polyclonal
Unconjugated
ST3GAL6
Liquid
ST3GAL6
A 16 amino acid peptide from near the carboxy terminus of human ST3gal6.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q9Y274, Q8VIB3, P61943
SIAT10, ST3GALVI; CMP-NeuAc:beta-galactoside alpha-2,3-sialyltransferase VI; ST3Gal VI; alpha2,3-sialyltransferase; sialyltransferase 10 (alpha-2,3-sialyltransferase VI); type 2 lactosamine alpha-2,3-sialyltransferase
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
10402, 304023, 54613
Documents
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