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LYK5 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA141207

Catalog No. 01-675-767


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Description

Description

Principal Names: LYK5; STE20-related Adaptor Protein (STRAD); FLJ90524; Official Gene Symbol: LYK5 Gene ID: 92335 (Human) Gene Map Locus: 17q23.3 (Human)  Members of STE-20 like kinase family are known to stimulate MAPK pathways by directly activating MAPKKK. STRAD is a novel pseudokinase member of this family consisting of a STE-20 like kinase domain but lacks several residues that are required for its catalytic activity. It specifically binds LKB1 and plays a key role in regulating tumor suppressor activities of LKB1. It functions as an upstream activator of LKB1 and also directs the sub-cellular localization of LKB1 by anchoring it in the cytoplasm. STRAD-LKB1 interaction results in phosphorylation of STRAD and enhanced autophosphorylation of LKB1.
Specifications

Specifications

LYK5
Polyclonal
Unconjugated
STRADA
Liquid
STRADA
Synthetic peptide corresponding to residues 300-350 of human STRAD (isoform 1).
Protein G
RUO
Antibody
Polyclonal
Human
Western Blot
0.5 mg/mL
PBS with 0.05% BSA and 0.05% sodium azide
Q7RTN6
STRAD
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
92335
Documents
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